Frido Graziani grew up in Peitrasanta, where he attended art school. After several years as assistant to the sculptor Umberto de Giovanni, he opened his own studio in 1940. At the same time he worked very closely with the most famous sculptors of the region.

Graziani models using clay and wax, and he prefers to work with bronze and marble. A focal point for him are portraits, especially of children. Graziani's works have almost never been shown in galleries and exhibitions, following his own desire. They are instead more commonly found in public spaces. One of his best known works is the sculpture "Kinder unterm Regenschirm" in the city of Neuchâtel.